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Blockchain in Healthcare: Use Cases, Benefits, and Costs

Shashikant Kalsha

September 1, 2025

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Introduction

The healthcare industry is one of the most data-intensive sectors in the world. From electronic health records (EHRs) and clinical trials to billing systems and insurance claims, healthcare generates vast amounts of sensitive data. Managing this data securely, efficiently, and transparently has always been a challenge.

Blockchain technology, best known as the foundation of cryptocurrencies like Bitcoin and Ethereum, is now transforming healthcare by addressing long-standing challenges such as data silos, fraud, and patient privacy. By offering a secure, immutable, and decentralized ledger, blockchain is unlocking new possibilities for better patient outcomes, reduced costs, and enhanced trust in healthcare systems.

In this article, we explore blockchain in healthcare, its use cases, benefits, costs, and examples of real-world implementations.

What is Blockchain in Healthcare?

Blockchain is a distributed ledger technology (DLT) where data is stored across multiple nodes, ensuring it cannot be altered or deleted. In healthcare, blockchain can securely manage patient records, supply chain data, and insurance transactions while maintaining privacy and compliance with regulations such as HIPAA (Health Insurance Portability and Accountability Act) in the USA and GDPR in Europe.

Key Features for Healthcare

  • Immutability: Patient records cannot be tampered with.

  • Decentralization: Eliminates single points of failure.

  • Transparency: Ensures accountability across providers and insurers.

  • Security: Data is encrypted and protected with cryptographic algorithms.

  • Smart Contracts: Automate claims, payments, and compliance processes.

Use Cases of Blockchain in Healthcare

1. Electronic Health Records (EHRs)

  • Problem: Patient data is fragmented across hospitals, clinics, and labs.

  • Solution: Blockchain enables a unified, secure, and accessible patient record that patients and authorized doctors can access anywhere.

Example: MIT’s MedRec project uses blockchain to manage medical record access permissions securely.

2. Pharmaceutical Supply Chain

  • Problem: Counterfeit drugs cost the global pharmaceutical industry an estimated $200 billion annually.

  • Solution: Blockchain can track drugs from manufacturer to pharmacy, ensuring authenticity.

Example: MediLedger helps track prescription drugs to prevent fraud in the U.S. pharmaceutical supply chain.

3. Clinical Trials and Research

  • Problem: Lack of transparency in trial results and data tampering undermine trust.

  • Solution: Blockchain records trial data immutably, making it tamper-proof and accessible to regulators.

Example: Pfizer and other pharma companies are exploring blockchain to ensure trial integrity.

4. Medical Billing and Insurance Claims

  • Problem: Fraudulent claims and administrative inefficiencies increase costs.

  • Solution: Smart contracts automate claims verification and settlement, reducing fraud and delays.

Example: Insurance startups are adopting blockchain-powered claims management platforms to cut costs and speed up processing.

5. Telemedicine and Remote Monitoring

  • Blockchain secures patient data shared through wearable devices and telemedicine apps. This ensures trust and compliance in remote healthcare.

6. Credentialing of Healthcare Professionals

  • Blockchain enables secure verification of doctor qualifications, licenses, and credentials, reducing fraud in hiring practices.

Benefits of Blockchain in Healthcare

  • Data Security and Privacy – Protects sensitive health data from hacks and breaches.

  • Interoperability – Enables seamless sharing of medical records across providers.

  • Transparency – Ensures accountability in clinical trials, billing, and supply chains.

  • Fraud Reduction – Minimizes counterfeit drugs and false insurance claims.

  • Patient Empowerment – Patients gain ownership of their health records.

  • Cost Efficiency – Reduces administrative overhead and operational inefficiencies.

Case Studies of Blockchain in Healthcare

1. IBM Blockchain & FDA Pilot

IBM partnered with the FDA to create a blockchain-based platform for sharing health data, including genomic information and clinical trial data.

Impact: Improved secure data exchange across multiple stakeholders.

2. Change Healthcare

A U.S.-based company leveraging blockchain to process medical claims more efficiently.

Impact: Reduced claim denials and fraud while streamlining billing.

3. Guardtime in Estonia

Estonia uses blockchain to secure the health records of its entire population.

Impact: Enhanced national-level healthcare security and efficiency.

4. MediLedger Network

Adopted by major pharmaceutical companies to track drug authenticity.

Impact: Strengthened compliance with the U.S. Drug Supply Chain Security Act (DSCSA).

Costs of Blockchain Implementation in Healthcare

Factors Influencing Cost

  • Complexity of Application: EHR systems cost more than supply chain pilots.

  • Blockchain Platform: Hyperledger Fabric, Ethereum, or Corda influence development costs.

  • Integration Needs: Connecting with existing hospital IT systems raises costs.

  • Regulatory Compliance: HIPAA and GDPR compliance add legal and security expenses.

  • Security Audits: Smart contract audits and penetration testing.

Average Cost Estimates (USA Market)

  • Pilot Blockchain Solution: $70,000 – $150,000

  • Medium-Scale Healthcare App: $200,000 – $400,000

  • Enterprise-Grade Solution (Hospital Networks, Pharma Giants): $500,000 – $1 million+

Challenges of Blockchain in Healthcare

  • Scalability: Handling massive healthcare datasets can strain blockchain networks.

  • Regulatory Uncertainty: Laws are evolving around blockchain and health data.

  • Adoption Resistance: Healthcare providers may resist new technologies.

  • Integration Issues: Legacy healthcare IT systems may not easily connect with blockchain.

Best Practices for Blockchain Adoption in Healthcare

  • Start with a Pilot Project – Validate blockchain use cases before scaling.

  • Collaborate with Stakeholders – Involve hospitals, insurers, regulators, and patients early.

  • Ensure Compliance – Prioritize HIPAA and GDPR compliance.

  • Invest in Security – Regular audits to prevent vulnerabilities.

  • Choose the Right Platform – Match blockchain platform to specific use cases.

Future Trends in Blockchain Healthcare

  • NFTs for Medical Data Ownership: Patients may tokenize and monetize their health data.

  • Integration with AI: AI + blockchain will drive predictive healthcare analytics.

  • Personalized Medicine: Blockchain-secured genomic data for tailored treatments.

  • National Blockchain Health Networks: Countries building nationwide blockchain health infrastructures.

Key Takeaways

  • Blockchain is solving long-standing healthcare challenges in security, transparency, and fraud prevention.

  • Use cases include EHRs, supply chains, clinical trials, and insurance claims.

  • Costs in the USA range from $70,000 for pilots to $1 million+ for enterprise systems.

  • Case studies from Estonia, IBM, and MediLedger demonstrate real-world impact.

  • Success requires compliance, collaboration, and careful platform selection.

Conclusion

Blockchain in healthcare is more than a buzzword—it’s a transformative technology redefining how health data is managed, shared, and secured. While costs can be high, the return on investment in terms of patient safety, fraud reduction, and efficiency makes blockchain adoption a strategic priority for forward-looking healthcare organizations.

As adoption grows, blockchain will not just secure health data but also empower patients, drive collaboration across the healthcare ecosystem, and pave the way for smarter, more personalized care.

About Qodequay

At Qodequay, we believe that meaningful innovation starts with understanding people. As a design-first company, we lead with deep empathy—immersing ourselves in the everyday realities, behaviors, and desires of your customers.

Only after decoding real-world pain points do we bring in technology as the enabler. This ensures every solution we build is not just technically sound, but intuitively aligned with human needs.

Whether it's:

  • Custom software for unique business challenges
  • Generative AI and automation to streamline operations
  • Immersive AR/VR/MR experiences
  • AI-powered CRM (QQCRM) for smarter customer engagement
  • EasyOKR to align teams and drive outcomes

We design with purpose, and build with precision.

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Shashikant Kalsha

As the CEO and Founder of Qodequay Technologies, I bring over 20 years of expertise in design thinking, consulting, and digital transformation. Our mission is to merge cutting-edge technologies like AI, Metaverse, AR/VR/MR, and Blockchain with human-centered design, serving global enterprises across the USA, Europe, India, and Australia. I specialize in creating impactful digital solutions, mentoring emerging designers, and leveraging data science to empower underserved communities in rural India. With a credential in Human-Centered Design and extensive experience in guiding product innovation, I’m dedicated to revolutionizing the digital landscape with visionary solutions.

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